Follows the adventures of Ogami Itto, a samurai framed and forced into exile with his infant son, as he pursues his quest for revenge against those who murdered his wife.
Aided by a female yakuza leader, Ogami Itto and his young son Daigoro continue towards Edo, and later the Yagyu clan offers an immense reward for the death of the Lone Wolf and his Cub, leaving them unable to trust anyone.